Publications

SITC 2019

RTX-321, an Allogeneic Artificial Antigen Presenting Cell (aAPC) Red Cell Therapeutic, Expressing MHC I-Peptide, 4-1BBL and IL-12, Promotes Expansion and Anti-Tumor Activity of Antigen-Specific T Cells in HPV16-Positive Tumors

Xuqing Zhang, Mengyao Luo, Shamael R. Dastagir, Mellissa Nixon, Albert Lee, Naren Subbiah, Douglas C. McLaughlin, Chris Moore, Sneha Pawar, Nicholas Bayhi, Timothy J. Lyford, Omkar Bhate, Viral Amin, Christopher L. Carpenter, Thomas J. Wickham, and Tiffany F. Chen

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AACR-NCI-EORTC 2019

Enabling the Rapid Generation of Allogeneic Artificial Antigen Presenting Cell (aAPC) Red Cell Therapeutics with a Loadable MHC System

Christopher L. Moore, Sneha Pawar, Mellissa Nixon, Timothy J. Lyford, Douglas C. McLaughlin, Shamael R. Dastagir, Christopher L. Carpenter, Thomas J. Wickham, and Tiffany F. Chen

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RNA Therapeutics Conference 2019

mRNA-based Engineering of Red Cell Therapeutics (RCTs) to Generate Potent, Allogeneic Cellular Therapies

Urjeet Khanwalkar, Sneha Hariharan, Clair Depew, Sivan Elloul, Zachary Koncki, Farris Nabulsi, Eric Finnemore, Arjun Bollampalli, Torben Straight Nissen, and Omid F. Harandi. Poster presented at the RNA Therapeutics Conference 2019: From Mechanism to Therapy on June 27, 2019, Worchester, MA.

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AACR 2019

RTX-240, an Allogeneic Red Cell Therapeutic Expressing 4-1BBL and IL-15TP, Exhibits Potent In Vitro and In Vivo Activity and a Favorable Safety Profile

Anne-Sophie Dugast, Shannon McArdel, Maegan Hoover, Enping Hong, Shannon Curtis Leonard, Arjun Bollampalli, Douglas C. McLaughlin, Jennifer Mellen, Torben Straight Nissen, Christopher L. Carpenter, Thomas J. Wickham, Lori Melançon, and Sivan Elloul. Poster presented at the American Association for Cancer Research (AACR) annual meeting on April 2, 2019, Atlanta, GA

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RTX-224, an Allogeneic Red Cell Therapeutic Expressing IL-12 and 4-1BBL, Exhibits Potent In Vitro and In Vivo Activity and a Favorable Safety Profile

Anne-Sophie Dugast, Enping Hong, Maegan Hoover, Arjun Bollampalli, Douglas C. McLaughlin, Omkar Bhate, Timothy J. Lyford, Torben Straight Nissen, Christopher L. Carpenter, Thomas J. Wickham, Lori Melançon, and Sivan Elloul. Poster presented at the American Association for Cancer Research (AACR) annual meeting on April 2, 2019, Atlanta, GA

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Engineered Red Cell Therapeutics (RCT) as Artificial Antigen Presenting Cells Promote and Antitumor Activity of Antigen Specific T Cells

Xuqing Zhang, Shamael R. Dastagir, Naren Subbiah, Mengyao Luo, Vikram Soman, Sneha Pawar, Douglas C. McLaughlin, Nicholas Bayhi, Viral Amin, Torben Straight Nissen, Christopher L. Carpenter, Thomas J. Wickham, Lori Melançon, and Tiffany F. Chen. Poster presented at the American Association for Cancer Research (AACR) annual meeting on April 2, 2019, Atlanta, GA

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